The first study examining the independent impact of remission and LDA definitions on damage accrual. INTRODUCTION Systemic lupus erythematosus (often called Lupus or SLE) is an autoimmune disease. It typically starts in women between the ages of 15 and 45. Lupus symptoms can vary from patient to patient. People with Lupus are often very tired, […]
Category: Lupus nephritis
Increased COVID-19 risk in autoimmune disease, but not more severe
People with autoimmune disease have an increased risk of getting infected with COVID-19, especially if they use steroid medicines. However, the risk of severe outcomes of COVID-19 such as hospitalisation or death is not increased. INTRODUCTION COVID-19 is the disease caused by a new type of coronavirus called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It […]
Managing lupus nephritis
This is the lay version of the 2019 update of the EULAR recommendations for the management of people with lupus nephritis. The original publication can be downloaded from the EULAR website: www.eular.org. Fanouriakis A, et al. 2019 Update of the Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA–EDTA) recommendations […]
Lupus may be more common than previously thought
These data challenge established views regarding the rarity of Lupus in both men and women. INTRODUCTION Systemic lupus erythematosus (often called Lupus or SLE) is an autoimmune disease. It typically affects women between the ages of 15 and 45. There are many things that can trigger Lupus, and symptoms can vary from patient to patient. […]
Blocking interferon results in clinical improvement for people with lupus
The type I interferon pathway contributes to the development of lupus. INTRODUCTION Systemic lupus erythematosus (also known as SLE or lupus) is an autoimmune disease. It typically affects women between the ages of 15 and 50, and symptoms flare up unpredictably. Lupus is caused by complicated interactions between the immune system and environmental factors leading […]
Treat to target may be a possibility in lupus in the near future
A composite definition of low disease activity in lupus may protect against poor outcomes. INTRODUCTION Systemic lupus erythematosus (also known as SLE or lupus) is an autoimmune disease. It typically affects women between the ages of 15 and 50, and symptoms flare up unpredictably. Lupus is caused by complicated interactions between the immune system and […]
Potential treatment for lupus nephritis without oral steroids
INTRODUCTION A small study of a new combination treatment for lupus nephritis that doesn’t include oral steroids has shown encouraging results. If larger studies show similar results, the new combination treatment could help people with this condition avoid the side effects of long-term treatment with high doses of oral steroids. WHAT DO WE KNOW ALREADY? Lupus nephritis […]
