Compared to other treatments, TNF inhibitors slowed radiologic progression significantly. INTRODUCTION Ankylosing spondylitis is a chronic inflammatory disease. It mainly affects the joints in the spine, and the sacroiliac joint (in the back part of the pelvis), causing back pain and stiffness. Some changes in ankylosing spondylitis are very slow. For example, the destruction of […]
Category: Ankylosing spondylitis
Secukinumab is effective in biologic-naïve and -experienced patients
Secukinumab provides sustained improvements in signs and symptoms of ankylosing spondylitis INTRODUCTION Spondyloarthritis is an umbrella term for several conditions that share many of the same features and symptoms, including ankylosing spondylitis, psoriatic arthritis and reactive arthritis. Patients can also be classified as having axial or non-axial (peripheral) disease, according to which joints in their […]
Disease activity and inflammation is linked to spinal damage, even in early disease
Disease activity is associated with radiographic spinal progression in early axial spondyloarthritis. INTRODUCTION Ankylosing spondylitis is a chronic inflammatory disease. It mainly involves the spine, but may be associated with other diseases, such as psoriasis (a skin disease), inflammatory bowel disease and uveitis (an inflammation in the eye). These non-joint symptoms are known as extra-articular […]
A quarter of patients do not agree with their doctor about their disease
Disagreement between people with early axial spondyloarthritis and their doctors happens in one-quarter of cases, and can affect how people are treated. INTRODUCTION Spondyloarthritis is an umbrella term for several conditions that share many of the same features and symptoms, including ankylosing spondylitis, psoriatic arthritis and reactive arthritis. Patients can also be classified as having […]
Continuous NSAID offers no benefit over on-demand in ankylosing spondylitis
More evidence is needed to confirm whether continuous NSAID can reduce joint damage in people with ankylosing spondylitis. INTRODUCTION Ankylosing spondylitis is a chronic inflammatory disease. It mainly involves the joints, but may be associated with other diseases, such as psoriasis (a skin disease), inflammatory bowel disease and uveitis (an inflammation in the eye). These […]
Ankylosing spondylitis is associated with skin, eye and bowel problems
The risk of developing uveitis, psoriasis and inflammatory bowel disease is increased in patients with ankylosing spondylitis. INTRODUCTION Ankylosing spondylitis is a chronic inflammatory disease that affects around 0.6% of people in western countries. It mainly involves the spine and large joints, but may be associated with other diseases, such as psoriasis (a skin disease), […]
New treatment targets for ankylosing spondylitis and psoriatic arthritis
INTRODUCTION A treatment approach based on clear targets for individual patients has helped relieve symptoms and improve quality of life for many people with rheumatoid arthritis. Now a report explains how the same approach could help people with other rheumatic conditions. WHAT DO WE KNOW ALREADY? Using clear treatment targets can help doctors and patients […]
