TNF inhibitors are associated with long-term risks and high costs; improving how they are used is therefore important. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints and sometimes their internal organs, causing pain and disability. It is more common in older people, and affects both men and women. Adalimumab and […]
Month: November 2016
Blocking interferon results in clinical improvement for people with lupus
The type I interferon pathway contributes to the development of lupus. INTRODUCTION Systemic lupus erythematosus (also known as SLE or lupus) is an autoimmune disease. It typically affects women between the ages of 15 and 50, and symptoms flare up unpredictably. Lupus is caused by complicated interactions between the immune system and environmental factors leading […]
Personalised medicine may be a possibility in Sjögren’s syndrome
People more likely to respond to rituximab treatment can be selected, making the treatment more focused and cost effective. INTRODUCTION Sjögren’s syndrome is an autoimmune disease. It typically affects the saliva and tear glands, causing dry mouth and eyes. Other parts of the body may also be drier than normal, and the disease can make […]
